منابع مشابه
Adipocyte Differentiation: When precursors are also regulators
As well as being the precursors of the triacylglycerols deposited as fat in adipose tissue, long-chain fatty acids are one class of agents that induce the differentiation of preadipocytes to adipocytes.
متن کاملDirecting visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice
Visceral adiposity confers significant risk for developing metabolic disease in obesity whereas preferential expansion of subcutaneous white adipose tissue (WAT) appears protective. Unlike subcutaneous WAT, visceral WAT is resistant to adopting a protective thermogenic phenotype characterized by the accumulation of Ucp1+ beige/BRITE adipocytes (termed 'browning'). In this study, we investigated...
متن کاملAdipocyte Precursors: Developmental Origins, Self-Renewal, and Plasticity
M.E. Symonds (ed.), Adipose Tissue Biology, DOI 10.1007/978-1-4614-0965-6_1, © Springer Science+Business Media, LLC 2012 Abstract The current epidemic of obesity and overweight has caused a surge of interest in the study of adipose tissue formation. Much progress has been made in defi ning the transcriptional networks controlling the terminal differentiation of preadipocytes into mature adipocy...
متن کاملOn circulant weighing matrices
Algebraic techniques are employed to obtain necessary conditions for the existence of certain circulant weighing matrices. As an application we rule out the existence of many circulant weighing matrices. We study orders n = 8 +8+1, for 10 ~ 8 ~ 25. These orders correspond to the number of points in a projective plane of order 8.
متن کاملHighly Selective In Vivo Labeling of Subcutaneous White Adipocyte Precursors with Prx1-Cre
The origins of individual fat depots are not well understood, and thus, the availability of tools useful for studying depot-specific adipose tissue development and function is limited. Cre drivers that selectively target only brown adipocyte, subcutaneous white adipocyte, or visceral white adipocyte precursors would have significant value because they could be used to selectively study individu...
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ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2014
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2013.10.003